生物節律紊亂體細胞克隆猴模型成功創建
生物節律紊亂體細胞克隆猴模型成功創建
  中科院腦科學與智能技術卓越創新中心/神經科學研究所和上海腦科學與類腦研究中心研究團隊利用體細胞克隆技術,獲得5只生物節律核心基因BMAL1缺失的克隆猴。這是國際上首次成功構建一批遺傳背景一致的生物節律紊亂獼猴模型,有助于推動人類腦疾病機理研究、早期診斷與干預及藥物研發等進程。
“深海勇士”號載人潛水器首征印度洋
“深海勇士”號載人潛水器首征印度洋
  2019年3月10日,“深海勇士”號載人潛水器完成為期121天的印度洋熱液科考航次。本航次中,“深海勇士”號經受惡劣海況和復雜海底地質環境嚴格考驗,刷新我國載人深潛史上單航次、單年、單月下潛作業次數等多項紀錄,為我國深入研究現代海底熱液流體系統的物質循環、生命演化和適應機制、生態環境效應提供了基礎。
抗腫瘤1類新藥鹽酸希美替尼獲準進入臨床研究
抗腫瘤1類新藥鹽酸希美替尼獲準進入
臨床研究
  2019年2月13日,由中科院藥物創新院相關課題組協作研發的抗腫瘤1類新藥鹽酸希美替尼(SOMCL-15-290)及其片劑,獲得國家藥品監督管理局頒發的臨床試驗通知書,獲準開展臨床試驗。鹽酸希美替尼具有自主知識產權,我國即將啟動臨床實驗患者篩選,美國新藥臨床研究(IND)申報正在準備中。
首次實現哺乳動物裸眼紅外圖像視覺感知能力
首次實現哺乳動物裸眼紅外圖像視覺
感知能力
  中國科大研究團隊利用自主發明的納米顆粒表面修飾方法,將可吸收紅外光發出可見光的上轉換納米材料導入動物視網膜,國際上首次使哺乳動物具備紅外圖像視覺感知能力,拓展了哺乳動物的視覺波譜范圍。利用該技術,通過開發具有不同吸收和發射光譜參數的納米材料,將有可能輔助修復紅色色盲等視覺感知波譜缺陷相關疾病。
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科學家建立“拓撲電子材料數據庫”
  中科院物理所研究團隊發展出自動計算材料拓撲性質新方法,原則上只需計算晶體材料能帶中高對稱點能帶的對稱性,即可獲得關于體系拓撲不變量部分甚至全部信息,大大簡化計算過程。利用該方法,研究團隊在近4萬種材料中發現8千余種拓撲材料,并在中科院計算機網絡信息中心支持下建立拓撲電子材料在線數據庫。
凡納濱對蝦基因組破譯成功
凡納濱對蝦基因組破譯成功
  由中科院海洋所研究人員主導的研究團隊,與國內外多家單位合作,歷時十年成功破譯凡納濱對蝦基因組,獲得國際首個高質量對蝦基因組參考圖譜。凡納濱對蝦作為四大養殖蝦類之首,具有重要的經濟價值。相關研究成果為甲殼動物研究及對蝦基因組育種和分子改良提供了重要理論支撐。
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